Heigl confirmed last month that she has decided to quit the programme to focus on her family.
A source has now told Us Weekly that the cast had clashed with Heigl and had been unhappy about the way she publicly criticised the show.
"Most of the cast and crew were like, 'Finally!'" the insider claimed. "There was such a release. With every movie, she'd get worse and start acting like she was the star."
The source added: "They're such a family and are glad to have this behind them. I doubt there will be a party to send her off."
However, Grey's Anatomy star Justin Chambers said earlier this week that Heigl is "much loved" by the cast.