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The doctors gather and learn that a plane has crashed into the sea. Seattle Grace is the designated crisis centre, where families will come to learn about their loved ones and any surviving patients will be brought. Owen starts organising their response and sending people off on jobs. Teddy rushes up to see Henry and tells him that his procedure will have been cancelled. She advises him what to do to make sure he is first in line when surgeries begin again and adds that she and Henry are not leaving until the plane crash is dealt with. Elsewhere, Mark complains that he has to work with Jackson, calling him an idiot for dropping out of Webber's trial. However, he is surprised when Owen tells him the truth - that Jackson was worried Webber wouldn't win the Harper Avery if he was involved. Meanwhile, Cristina goes to see Alex and tells him Meredith was the only one who cared about him. She warns that no-one would even give him a glass of water in a burning building now. Alex goes to see Owen and explains he was drunk when he told him about Meredith. He adds that he doesn't think she should be chief resident but didn't think she would be fired. Owen replies that if he didn't realise she would be, he is as dumb as Meredith. In the cafeteria, families start arriving and are desperate for news, even though there is none. Eli spots Bailey looking upset and she admits that she has taken the same flight a number of times with her son. She insists she's OK and doesn't have time to sit down, but Eli stays with her for a while. Elsewhere, Cristina starts interviewing a patient and asks if she could be pregnant. She has to prompt her to remember when she had her last period but as she talks, Cristina has a sudden realisation. She goes to see Lucy, who confirms that Cristina is about six weeks pregnant.

Webber, Derek and Meredith go to talk about the trial but Meredith refuses to say anything. She explains that the trial will only become invalid once she does as they still don't know what happened. She tells them again to fire her, but Derek yells that she doesn't get to decide who gets the drug and who gets the placebo. He adds that she screwed him and the hospital, saying he was trying to cure her disease. Alex arrives and hands Webber a file, and the Chief suddenly realises that Meredith ensured Adele got the drug. Derek asks what he's going to do, adding that the protocol is clear. Meredith is shocked that he is encouraging Webber to fire her, but Webber admits that he basically pressured Meredith to make sure Adele got the drug. He suspends her so it doesn't look bad and admits he will have to turn the trial over to the FDA. Derek walks out and Webber appears to be trying to thank Meredith, although he can't do it explicitly. Later, Meredith has to go and see the patient with young children to tell him that he probably won't be getting the treatment now. His wife is furious, yelling that they could treat her husband if they wanted to and shouting that her children's father is disappearing.

Later, Owen goes to sit outside with Cristina and they continue to chat about Cristina's pregnancy. Owen says he could take leave to look after the baby and Cristina wouldn't have to worry about it. However, Cristina says that she's not a monster and would love a baby if she had it - she couldn't just ignore it. Owen finds it amusing that her big problem is that she would love her baby but Cristina accuses him of not listening to her. She says they can't compromise over this - you can't have half a baby. She says she just doesn't want to be a mother. Owen asks if she loves and trusts him and explains that he thinks she will be a great mother. Cristina asks why she would have this baby and Owen says because she loves him. Meanwhile, Teddy goes to see Henry and admits that she has had a tough time telling the families that their relatives have died in the crash. Henry says he has tried to be a gentleman but tells her to get out of his room. He shouts that the hardest and most painful thing he has had to do was letting her go and yells that he's in love with her. He says he's not her best friend or security blanket and asks her to leave him alone. Teddy walks out crying.
Meanwhile, April is shocked to learn that there is a survivor from the plane crash. It's a young girl who was flying alone - an unaccompanied minor. The doctors rush to take care of her and April goes to see if she has any family members in the cafeteria. The cafeteria is full of families in tears, contacting relatives to explain their loss. When one of the grieving mothers hears that a young girl has survived - and none of her family members are at the hospital yet - she decides that she will stay. She tearfully explains that she wouldn't have wanted her son to be alone. Her husband agrees and all of the other families stay as well. Lexie promises to let them know how the girl is doing.
Derek finds Meredith, who reveals that she didn't get fired and adds that he's probably disappointed. Derek points out that he's not the bad guy and yells that if Meredith had been thinking about all the people with Alzheimer's they could have helped she would never have done this. He says she doesn't know the difference between right and wrong, but Meredith believes things are more complicated than that. Derek tells her that he doesn't know how to raise a child with someone who doesn't know the difference between right and wrong. Meredith asks if he's saying she's a bad mother, and Derek points out that she's been saying that for weeks and maybe she's right. He says he needs some space and walks off. At that moment, Meredith reads a text from her social worker, saying they need to discuss the adoption. Later, Cristina tries to talk to Meredith but Meredith is preoccupied - the adoption lady is paging her and Derek's missing and not speaking to her. She explains that she was thinking about Adele when she tampered with the trial. Cristina continues to try to talk to Meredith, but Meredith is shocked to see Alex talking to the social worker, Janet. She goes over to interrupt but Alex insists he hasn't said anything bad. Janet announces that she's granting Meredith temporary custody of Zola until she's granted permanent custody. She says Alex has said Zola is doing well so Meredith can take her home today.


Cristina arrives home and, asking Owen to remember that he loves her, reveals that she has made an appointment to have an abortion. She says she needs to lie down as she feels unwell, but Owen is furious that she decided without him. Owen says he's made sacrifices and he wanted Cristina to consider doing something for him, but she yells that it's a baby - you don't "give a little" on a baby. Again, she refuses to go through with the pregnancy and Owen yells at her to leave as she shut him out of the decision. Cristina goes to stay at Meredith's house. Meredith reveals that Derek has gone and she has Zola upstairs. She is shocked to discover that Cristina is pregnant, having an abortion, and Owen kicked her out. Cristina explains that she didn't tell her because Meredith had a busy day. Zola starts crying and Meredith asks Cristina to come up and help her, but Cristina says she can't be around a baby and goes to lie down. The episode ends with Derek at the building site, looking at the marks setting out where the crib would go. He lies down with a sleeping bag.
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