Major cast changes for new 'Prison Break'

At least one major character will reportedly be killed off during the fourth season premiere of Prison Break, with two new cast members joining the show.

E! Online states that a Fox representative has confirmed that "at least one actor will be leaving the series for good" and that their identity will be a "genuine surprise" to viewers.

Executive producer Zack Estrin has also revealed details of two new characters and how they relate to former fugitives Michael Scofield and Lincoln Burrows.

Cress Williams will play Wyatt, who Estrin describes as a "Company guy who is... hot on our guys' tail. When the season begins, there is a cover story that our guys are placed into a SuperMax prison and slowly but surely, clues are coming out that they aren't in there - that they're up to something else maybe. This guy's job is to find out what they're really up to."

Meanwhile, James Hiroyuki Liao will play hacker Roland, "a new guy they're forced to work with, and they're not sure how they feel about him, but they need his expertise in the technological stuff that our guys don't necessarily do".

Prison Break will return to Sky One in early September.