While speaking at the Television Critics' Association summer press tour, Laurie told reporters that the actress, who chose to exit the show in May, is missed on the medical drama, TV Line reports.
"We all miss Lisa very much," Laurie admitted.
Laurie went on to tease the eighth season of House, revealing that his character will be in prison at the beginning of the season.
"I am a prisoner," he said. "I don't know [how long I'll be there]. They keep me in the dark. It's probably better that way."
In June, it was announced that Edelstein had signed on to The Good Wife for a multi-episode arc.
House creator David Shore previously said that he was "really disappointed" by Edelstein's departure from the show, confessing that he would have altered the season finale if he had known of her decision.
House returns October 3 on Fox.