The one-and-a-half-minute clip features an explosive battle between Sookie, Bill, Eric and co against the return of Russell Edgington and a new vampire group called The Authority.
Watch the trailer below:
The trailer begins with Sookie (Anna Paquin) and others dealing with Tara (Rutina Wesley)'s shooting. Tara does not feature in the trailer, though she did receive her own character poster last week, which questions her involvement in the season.
Eric (Alexander Skarsgård) tells Sookie: "The end may come soon. Either Russell will have our heads, or The Authority will."
Other scenes include the arrival of new character Roman (Christopher Meloni), Reverend Newlin (Michael McMillian) wanting to farm humans, Sam Merlotte (Sam Trammell) firing a crossbow, Sookie getting close to Alcide (Joe Manganiello) and Hoyt (Jim Parrack) seemingly getting bitten by a vampire.
Grey's Anatomy actor Scott Foley has also joined the cast of the fantasy series for its fifth run.
The fifth season premieres on HBO on June 10. It will air on FX in the UK later this year.