The former Heroes star appeared in four episodes of the Showtime drama's sixth season as lab intern Ryan Chambers.
"I would love to go back," she told FEARnet. "I didn't feel like my character had much closure."
Grant added that her Dexter stint was always intended to be a four-episode run.
"They kind of always knew my character was going to go in episode four. [But] I'd like to think that people love me and I became very memorable and they want to bring me back. I hope they bring me back.
"With Heroes, I was supposed to be there for two episodes, but they liked me, and I ended up doing seventeen."
Jennifer Carpenter - who plays Dexter's sister Deb - recently confirmed to Digital Spy that the show's eighth season will be its last.
A seventh season of Dexter will premiere on Sunday, September 30 at 9/8c.
> Dexter Michael C Hall: 'All bets are off in season seven'
Watch Jennifer Carpenter discuss Dexter with Digital Spy below: