The ABC show was axed after four seasons at the beginning of the year.
"It was heartbreaking," Williams told What's On TV. "We finally got the show perfect and running smoothly, then the rug was pulled from under us. But playing Wilhelmina gave me four tremendous years."
However, Williams explained that she has enjoyed playing Renee on Desperate Housewives.
"Everyone has been tremendously welcoming," she said. "I love being on Desperate Housewives. It has really revolutionised television with its portrayal of women my age."
Desperate Housewives airs on Sundays at 9/8c on ABC.