The 30-year-old high school swim coach was nominated alongside Jordan Lloyd this week when veteran Daniele Donato won the third Head of Household competition and decided to take revenge for his decision to separate her from friend Dominic Briones.
While Rachel Reilly was initially on the placed on the chopping block with Villegas, his victory in the Power of Veto competition allowed him to save her, forcing Donato to announce Lloyd as a replacement nominee.
Four out of seven voting houseguests voted to eliminate Villegas, with only his fiancée Rachel Reilly and alliance member Porsche Briggs attempting to spare him from eviction.
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Speaking to host Julie Chen after leaving the house, Villegas said that he did not regret his decision to save Reilly and that he would make the same choice if faced with the predicament again.
"Well, you know, it's a crazy thing. She's everything to me and I would do it a thousand times over. She would have done it for me last year without hesitance, so I would do it again in a day," he explained.
"There's two parts. Obviously I would do it for her cos she is the love of my life but I also know up against anyone else in the house, she had a bigger chance of going than I did. Not much, but a little bit."
Julie also questioned Villegas on his thoughts regarding former alliance member Donato's vendetta against him.
"I think it was a huge mistake. I think it was the same thing with her year. There was a certain point when we told her that we could all work together and try to stay in this competition and one of us could make the final two," he said.
"I think she's still living in her dad's shadow and I think that's a big burden on her shoulders. I honestly think that she'll make it for a few more weeks but she'll be taken out."
Big Brother continues on Sunday at 8/7c on CBS.