Richards is best known for appearing on Bravo's Real Housewives of Beverly Hills opposite her sister Kim, but also works as an actress.
The 43-year-old will play wealthy divorcée Ms Young in an upcoming CSI episode, TV Guide reports.
When Young's neighbour is killed, she is drawn into a murder inquiry and is questioned by Julie Finlay (Elisabeth Shue).
Richards previously played the recurring role of Nurse Dori on ER between 1998 and 2006 and also starred on Little House on the Prairie from 1975 to 1982.
CSI returns to CBS on Wednesday, September 26 at 10/9c. In the UK, the series airs on both Sky Living and Channel 5.
> CSI star William Petersen quits Cinemax pilot Hurt People
> Desperate Housewives' Neal McDonough for CSI: NY
Watch a CSI video recap below: