The CW drama's sixth run - confirmed as its last - will focus on the show's "core characters".
"The gang that you see in the final act [of the fifth season finale] will be our main players," Savage told The Hollywood Reporter. "We're definitely focusing on our core characters."
However, Savage refused to confirm if the Gossip Girl writing team have already devised the show's ending.
"We know a lot of things [about how it ends]," she hinted.
The final season of Gossip Girl will also be comprised of fewer episodes than usual, Savage confirmed.
"Right now, they're saying 10 episodes and a retrospective," said the show exec, adding that a final decision on the episode count is yet to be made.
The Gossip Girl season five finale 'The Return of the Ring' aired last night (May 14) on The CW. In the UK, the series continues on ITV2.