Snooki, whose real name is Nicole Polizzi, told E! News that she does not want to be inside the room while she is pregnant.
"I'm definitely taking this pregnancy seriously," she said.
"And with all the bacteria and everyone having sex in the smoosh room, it's just not where a pregnant person or a baby should be."
Snooki's comments come after reports that she will not be living in the beachfront Jersey Shore house with the other stars in the show's upcoming sixth season.
A source told E! News that the plan is for Snooki to "live close by" but a spokesperson for MTV refused to comment on the rumours.
"We don't comment on series in production," the representative said. "You can refer back to MTV's original statement, which was that all eight cast members are making a return."
Snooki's Jersey Shore spinoff with her co-star Jenni 'JWoww' Farley, Snooki & JWoww, is due to premiere on MTV on June 21.