The professional dancer told Hollyscoop that while next season's Dancing cast has yet to be finalised, she would love to work with Stamos as she believes he would be a good fit for the series.
Smirnoff said: "Definitely John Stamos [would be great to work with]. I think he's got the looks, He's got the experience of being on-stage, doing Broadway."
Smirnoff also responded to rumours that Lindsay Lohan's mother Dina could join the Dancing with the Stars roster, admitting that she "wouldn't be surprised" to see Dina on the dance floor.
"You know, I've heard about Dina Lohan wanting to be on the show for a few seasons now and, you know, the Lohan family is very outspoken and they're always present in the press, so I wouldn't be surprised if at least one of the Lohans ends up on Dancing with the Stars," Smirnoff explained.
Dancing with the Stars will return for its 13th season on September 19 on ABC.