The Green Bay Packers star explained that the physicality of both football and competitive dancing can take a real toll on the body.
"[Dancing with the Stars and football are] about the same," Driver told Access Hollywood. "I mean, on the football field you can twist an ankle, in dancing you can twist an ankle. You can get a shoulder injury trying to pick someone up, you can get a shoulder injury by playing football and getting hit."
The former All-Pro wide receiver added: "It all transitions - just in a different way. But I haven't done anything wrong at this point and I hope I don't, so I'm pretty healthy and I'm hoping I can stay that way."
Driver was called a "diamond on the rough" by judge Bruno Tonioli during Monday's Dancing with the Stars premiere, with the athlete and his partner Peta Murgatroyd earning a 21 out of 30 for their cha cha.
Dancing with the Stars continues next Monday (March 26) at 8/7c on ABC.
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Watch Donald Driver and Peta Murgatroyd's cha cha routine below: